A proper analysis of pharmacokinetic (PK) data can have incredible implications. Something to think about is how the data should be prepared prior to any statistical analysis. This brings me to the goal of this post – to log or not to log, that is thy question. The short answer is yes, PK parameters shouldContinue reading “Pharmacokinetic Parameters – To log transform or not to log transform”
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The Cutaneous Anatomy
Before we dive into cutaneous pharmacokinetics (PK), methods to quantify API concentrations over time, and develop new concepts, we need to understand the cutaneous anatomy. If you are relatively unfamiliar with cutaneous PK, this will help when I mention specific stratifications, such as the stratum corneum or dermal adipocytes, in future posts. While this willContinue reading “The Cutaneous Anatomy”
My First Publication!
I am super excited that my first publication is in the books! In this paper, we evaluated the local bioavailability from topical dermatological drug products containing metronidazole using dermal microdialysis. This might be a methodology to evaluate cutaneous pharmacokinetics. I don’t want to give away the entire story before you read it so come checkContinue reading “My First Publication!”
Pharmacokinetics with Ben Kuzma 